Renee JiJi and Jason Cooley work together at the University of Missouri (MU), Columbia, and have a daughter at home. The two met in graduate school and got married when they were postdocs living apart—she in Washington, D.C., and he in Philadelphia. JiJi began a tenure-track faculty position in the MU chemistry department in 2005; Cooley followed suit a year and a half later. JiJi and Cooley sat down for a conversation about working with a spouse and their different experiences traveling similar paths. Their comments have been edited for brevity and clarity.